Sarah Holbrook

2 weeks ago | therobinreport.com | Sarah Holbrook

When President Trump stood next to his super-sized tariffs chart on April 2nd, he looked wholly satisfied as he actualized his very own shock and awe moment. The world was expecting tariffs, but not a worldwide economic cataclysm. Now, the globe is in the throes of motion sickness as the tariff yo-yo continues to wind and unwind, following an all too predictable pattern. The time to start drawing the roadmap for the coming 24 months and beyond is now.

2 months ago | therobinreport.com | Sarah Holbrook

Doing business in Spring 2025 is not for the faint of heart. The recent economic (and other) shockwaves serve as a reminder that the future does not proceed from the past along a neat and projectable trajectory. Until we learn to anticipate disruption and be prepared, we will continue to face new dilemmas that look a lot like today’s as we await the thwack of the descending sledgehammer that is the ever-evolving U.S. tariff gambit.

Jan 23, 2025 | therobinreport.com | Sarah Holbrook

Our observation is that the over 1000 one-off solutions at the show confuse more than provide clarity on how to integrate so many systems and solutions into an integrated whole. The AI hype was unavoidable, but the how-to was convoluted at best. The acres of AI-infused technology displayed on the expo floor won’t result in any significant breakthroughs when deployed in a vacuum. The value will be realized when AI applications adapt and evolve to work together as a holistic connected system.

Aug 24, 2024 | biorxiv.org | Hao-Chih Hung |Carlos Costas-Insua |Sarah Holbrook |Jennifer Stauffer

AbstractThe surveillance of translation is critical for the fitness of organisms from bacteria to humans. Ribosome-associated Quality Control (RQC) is a surveillance mechanism that promotes the elimination of truncated polypeptides, byproducts of ribosome stalling during translation. In canonical mammalian RQC, NEMF binds to the large ribosomal subunit and recruits the E3 ubiquitin ligase Listerin, which marks the nascent-chains for proteasomal degradation.

Jun 26, 2024 | therobinreport.com | Sarah Holbrook

Walmart persists in its unrelenting cycle of innovation as retail’s battle royale between the mega-retailer and its rival Amazon continues. Yes, but it begs the question that if this duopoly at the top continues, what does this mean for the future of retail? Will tomorrow’s shopper be presented with a consumer landscape dominated by two commercial titans and a few trailing wannabes?