Scott H. Sicherer

1 month ago | hcplive.com | Chelsie Derman |Scott H. Sicherer

At the 2025 American Academy of Allergy, Asthma, & Immunology (AAAAI) in San Diego, Scott Sicherer, MD, from Mt. Sinai School of Medicine, presented the late breaker, “Randomized Trial of High Dose, Home Measured Peanut Oral Immunotherapy in Children with High Threshold Peanut Allergy.” His team’s phase 2 trial compared the tolerance levels of peanut oral immunotherapy vs avoiding peanuts altogether in 73 children aged 4 – 11 years with a high threshold peanut allergy (> 143 mg) The study...

Oct 4, 2024 | onlinelibrary.wiley.com | Scott H. Sicherer

EAACI European Academy of Allergy, Asthma, and Clinical Immunology EPIT epicutaneous immunotherapy GRADE Grading of Recommendations, Assessment, Development, and Evaluation OIT oral immunotherapy SLIT sublingual immunotherapy In 1908, Alfred Schofield described treating a 13 year old with severe egg allergy with increasing amounts of egg for “establishing tolerance to this special poison.”1 In 2014, the EAACI guidelines stated that food immunotherapy was not recommended for routine clinical...

Apr 19, 2024 | healio.com | Richard Gawel |Kristen Dowd |Scott H. Sicherer

Scott H. Sicherer, MD, FAAP These findings are significant as a concept that can be further developed. People in this field have been thinking about various approaches as a potential “gateway drug” toward OIT. OIT is a robust therapy that can raise thresholds, potentially quite significantly, but carries frequent adverse events, especially for those most sensitive.

Feb 12, 2024 | healio.com | Richard Gawel |Marc E. Rothenberg |Scott H. Sicherer

You've successfully added to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Healio compiled the most-read news in allergy, asthma and immunology posted in January.

Jan 29, 2024 | healio.com | Richard Gawel |Kristen Dowd |Scott H. Sicherer

Scott H. Sicherer, MD, FAAP With so few OIT studies in adults, even this small group adds significantly to knowledge about OIT and “long-term” outcomes. It is significant also that the study focused on staple dietary foods, namely milk and egg, as well as peanut. It has to be appreciated that almost all of the participants were very sensitive at the start, with most reacting to what we would call “trace” exposure and having very strongly positive allergy tests.