Seema Riyaz

Sep 14, 2024 | biorxiv.org | Ananya Sarkar |Poornima Menon |Deepa Ajnar |Seema Riyaz

AbstractAutophagy Conjugation machinery forms a center piece of autophagy and is essential for sequestration of a broad range of cargo destined for degradation. Apart from its role in canonical autophagy, recent evidence suggests an unconventional role of conjugation machinery. Membrane Atg8ylation is one of the manifestations of autophagy, wherein ATG8 conjugation machinery recruit mammalian ATG8s (mATG8s) to the damaged membranes for repair or removal.