Sepehr Shirani

Sep 23, 2023 | biorxiv.org | Bahman Abdi-Sargezeh |Abhinav Sharma |Philip A Starr |Sepehr Shirani

AbstractNeural activities within the beta frequency range (13-30 Hz) are not stationary, but occur in transient packets known as beta bursts. Parkinson's disease (PD) is characterized by the occurrence of beta bursts of increased duration and amplitude within the cortico-basal ganglia network. The pathophysiological importance of beta bursts is exemplified by the fact that they serve as a clinically useful feedback signal in beta amplitude triggered adaptive Deep Brain Stimulation (aDBS).