Seppe Goovaerts

Dec 2, 2024 | journals.plos.org | Meng Yuan |KU Leuven |Hospitals Gasthuisberg Leuven |Seppe Goovaerts

Citation: Yuan M, Goovaerts S, Vanneste M, Matthews H, Hoskens H, Richmond S, et al. (2024) Mapping genes for human face shape: Exploration of univariate phenotyping strategies. PLoS Comput Biol 20(12): e1012617. https://doi.org/10.1371/journal.pcbi.1012617Editor: Xin He, University of Chicago Pritzker School of Medicine, UNITED STATES OF AMERICAReceived: April 7, 2024; Accepted: November 5, 2024; Published: December 2, 2024Copyright: © 2024 Yuan et al.

Sep 17, 2024 | journals.plos.org | Seppe Goovaerts |KU Leuven |Hospitals Gasthuisberg Leuven |Myoung Keun Lee

Citation: Goovaerts S, El Sergani AM, Lee MK, Shaffer JR, Claes P, Weinberg SM (2024) The impact of breastfeeding on facial appearance in adolescent children. PLoS ONE 19(9): e0310538. https://doi.org/10.1371/journal.pone.0310538Editor: James J. Cray Jr., Ohio State University, UNITED STATES OF AMERICAReceived: March 14, 2024; Accepted: September 3, 2024; Published: September 17, 2024Copyright: © 2024 Goovaerts et al.

Nov 15, 2023 | nature.com | Seppe Goovaerts |Meng Yuan |Sahin Naqvi |Paul A. Romitti |Mary L. Marazita |John R. Shaffer | +2 more

AbstractThe cranial vault in humans is highly variable, clinically relevant, and heritable, yet its genetic architecture remains poorly understood. Here, we conduct a joint multi-ancestry and admixed multivariate genome-wide association study on 3D cranial vault shape extracted from magnetic resonance images of 6772 children from the ABCD study cohort yielding 30 genome-wide significant loci.

Aug 14, 2023 | biorxiv.org | Meng Yuan |Seppe Goovaerts |Hanne Hoskens |Stephen M. Richmond

AbstractA genome-wide association study (GWAS) of a complex, multi-dimensional morphological trait, such as the human face, typically relies on predefined and simplified phenotypic measurements, such as inter-landmark distances and angles. These measures are predominantly designed by human experts based on perceived biological or clinical knowledge.