Serena M. Pulente

Aug 24, 2024 | biorxiv.org | Luke Kennedy |Tyler Smith |Stephanie Myers |Serena M. Pulente

AbstractOPA1 is an inner mitochondrial membrane protein that mediates diverse signaling processes. OPA1 is important for cardiac function and protects against cardiac insults such as ischemia reperfusion injury. We sought to further assess OPA1 in human and mouse cardiac pathologies, hypothesizing that OPA1 may also function in a protective manner in chronic heart failure.