Seungsoo Kim

Jun 7, 2024 | journals.plos.org | Juan Bravo |Chanelle R Mizrahi |Seungsoo Kim |Lucia Zhang

Loading metrics Open Access Peer-reviewedResearch Article ? This is an uncorrected proof. Citation: Bravo JI, Mizrahi CR, Kim S, Zhang L, Suh Y, Benayoun BA (2024) An eQTL-based approach reveals candidate regulators of LINE-1 RNA levels in lymphoblastoid cells. PLoS Genet 20(6): e1011311. https://doi.org/10.1371/journal.pgen.1011311Editor: Scott M.

May 29, 2024 | biorxiv.org | Sahin Naqvi |Seungsoo Kim |Saman Tabatabaee |Anusri Pampari

AbstractDeep learning approaches have made significant advances in predicting cell type-specific chromatin patterns from the identity and arrangement of transcription factor (TF) binding motifs. However, most models have been applied in unperturbed contexts, precluding a predictive understanding of how chromatin state responds to TF perturbation.

Nov 29, 2023 | biorxiv.org | Juan Bravo |Chanelle R Mizrahi |Seungsoo Kim |Lucia Zhang

AbstractLong interspersed element 1 (L1) are a family of autonomous, actively mobile transposons that occupy ~17% of the human genome. A number of pleiotropic effects induced by L1 (promoting genome instability, inflammation, or cellular senescence) have been observed, and L1's contributions to aging and aging diseases is an area of active research. However, because of the cell type-specific nature of transposon control, the catalogue of L1 regulators remains incomplete.

Aug 17, 2023 | biorxiv.org | Juan Bravo |Seungsoo Kim |Chanelle R Mizrahi |Lucia Zhang

AbstractLong interspersed element 1 (L1) are a family of autonomous, actively mobile transposons that occupy ~17% of the human genome. The pleiotropic effects L1 induces in host cells - promoting genome instability, inflammation, or cellular senescence - are established, and L1's associations with aging and aging diseases are widely recognized. However, because of the cell type-specific nature of transposon control, the catalogue of L1 regulators remains incomplete.

May 29, 2023 | biorxiv.org | Seungsoo Kim |Ekaterina Morgunova |Sahin Naqvi |Maram Bader

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