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Dec 1, 2024 | 
nature.com | Shan Gao
AbstractAerobic glycolysis is a hallmark of cancer and is regulated by growth factors, protein kinases and transcription factors. However, it remains poorly understood how these components interact to regulate aerobic glycolysis coordinately. Here, we show that sine oculis homeobox 1 (SIX1) phosphorylation integrates growth factors (e.g. TGFβ, EGF) to control aerobic glycolysis and determines its tumor-promoting activity.
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Oct 15, 2024 | 
onlinelibrary.wiley.com | Dagui Wang |Wei Zhang |Shan Gao |Zhenda Liu
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202406072-sup-0001-SuppMat.docx23.3 MB Supporting Information smll202406072-sup-0002-MovieS1.mp46.9 MB Supplemental Movie 1 smll202406072-sup-0003-MovieS2.mp431.3 MB Supplemental Movie 2 smll202406072-sup-0004-MovieS3.mp49.3 MB Supplemental Movie 3 smll202406072-sup-0005-MovieS4.mp47.6 MB Supplemental Movie 4 References 1a) , , , , , , Adv.
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Aug 29, 2024 | 
dx.doi.org | Shan Gao |Lin Li |Yunqing Tang |Ping Yang
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Jul 5, 2024 | 
biorxiv.org | Yue Yang |Hongtu Zhu |Kaixian Yu |Shan Gao
AbstractBackground: Alzheimer disease (AD), a progressive neurodegenerative disorder, continues to increase in prevalence without any effective treatments to date. In this context, knowledge graphs (KGs) have emerged as a pivotal tool in biomedical research, offering new perspectives on drug repurposing and biomarker discovery by analyzing intricate network structures.
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Jun 26, 2024 | 
pubs.rsc.org | Li Yu |Shan Gao |Ruotong Li |Wenjun Tai
The microsyringe-assisted visual volume detection based on phase separation: The case of chymosin milk-clotting activity study
The constantly diverse demand scenarios for rapid on-site analysis have put forward high requirements for developing low-cost and user-friendly visual detection methods.
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Apr 22, 2024 | 
philsci-archive.pitt.edu | Shan Gao
Gao, Shan (2024)Why the global phase is not real. Foundations of Physics, 54 (19). ISSN 1572-9516 This is the latest version of this item. Textphase unreal 2024.pdf Download (207kB) | Preview Abstract In this paper, I present a new analysis of the meaning of the phase in quantum mechanics. First, I give a simple but rigorous proof that the global phase is not real in psi-ontic quantum theories.
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Oct 19, 2023 | 
nature.com | Shan Gao |J. Julio Camarero |Flurin Babst
AbstractAlthough the global climate is warming, external forcing driven by explosive volcanic eruptions may still cause abrupt cooling. The 1809 and 1815 Tambora eruptions caused lasting cold extremes worldwide, providing a unique lens that allows us to investigate the magnitude of global forest resilience to and recovery from volcanic cooling.
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Jul 31, 2023 | 
frontiersin.org | Bing Bai |Shan Gao |Nan Zhou
Chao Li1,2 Denghong Chen1,2 Ke Yang2*1School of Mining Engineering, Anhui University of Science and Technology, Huainan, China2Energy Research Institute of Hefei Comprehensive National Science Center (Anhui Energy Laboratory), Hefei, ChinaIn this paper, the authors address the issue of large solid waste output and surface subsidence in the western coal base.
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Jul 20, 2023 | 
mdpi.com | Shan Gao |Kainan Huang |Wenchao Chu |Wensheng Wang
Abstract:Concrete with light weight and pervious performance has been widely recognized as an effective and sustainable solution for reducing the negative impacts of urbanization on the environment, as it plays a positive role in urban road drainage, alleviating the urban heat island effect and thermal insulation, as well as seismic performance, etc. This research paper presents a feasibility study of pervious concrete preparation with ceramsite as aggregate.
