Shaopeng Yang

Jan 14, 2025 | nature.com | Shaopeng Yang |Wenyong Huang |Lei Zhang

AbstractPhotoreceptors are specialized neurons at the core of the retina’s functionality, with optical accessibility and exceptional sensitivity to systemic metabolic stresses. Here we show the ability of risk-free, in vivo photoreceptor assessment as a window into systemic health and identify shared metabolic underpinnings of photoreceptor degeneration and multisystem health outcomes.

Oct 18, 2023 | nature.com | Shaopeng Yang

AbstractThe retina is an important target organ of diabetes mellitus, with increasing evidence from patients and animal models suggesting that retinal pigment epithelium (RPE) may serve as an early marker for diabetes-related damages. However, their longitudinal relationship and the biological underpinnings remain less well understood.