Shawn R Starkenburg

Jun 10, 2024 | nature.com | Vrinda Venu |Cullen Roth |Eric Small |Shawn R Starkenburg |Karissa Y. Sanbonmatsu

AbstractThe genome folds into complex configurations and structures thought to profoundly impact its function. The intricacies of this dynamic structure-function relationship are not well understood particularly in the context of viral infection. To unravel this interplay, here we provide a comprehensive investigation of simultaneous host chromatin structural (via Hi-C and ATAC-seq) and functional changes (via RNA-seq) in response to vaccinia virus infection.