Shichao Lv

Nov 7, 2023 | aging-us.com | Yanyang Li |Lu Fan |Xiaoming Wang |Shichao Lv

Research Paper Volume 15, Issue 21 pp 12400—12412 1 Department of Integrated Traditional and Western Medicine, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China 2 National Clinical Research Center for Cancer, Tianjin 300060, China 3 Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China 4 Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China 5 First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin...

Nov 7, 2023 | aging-us.com | Yanyang Li |Lu Fan |Xiaoming Wang |Shichao Lv

Context: Autophagy-apoptosis is the core mechanism of doxorubicin-induced myocardial injury. miR-30a is a pivotal factor in the regulation of autophagy and apoptosis. It remains unclear whether SMI exerts cardioprotective effect by regulating autophagy and apoptosis via miR-30a. Objective: This study evaluates the effects of SMI on ameliorating doxorubicin-induced myocardial injury. Materials and Methods: The level of LDH and CK, and the expression of miR-30a was detected.

Jul 10, 2023 | frontiersin.org | Julio Plaza-Díaz |Shichao Lv |Xiaoyan Liu

1. IntroductionHeart failure (HF) is a common global heart disease with high morbidity and mortality rates, which is a clinical syndrome characterized by abnormal cardiac structure and function (McDonagh et al., 2022). Recent studies have shown that the inflammatory response (Murphy et al., 2020), myocardial interstitial fibrosis (González et al., 2018), apoptosis (Liao et al., 2022) and calcium signaling (Kubalova et al., 2005) promote the development of HF.

Jun 15, 2023 | frontiersin.org | Jinbo Xiong |Shichao Lv |Zang-xiang Teaching

1. Introduction Heart failure (HF) can arise from structural or functional abnormalities of the heart due to various reasons and is the final stage of multiple cardiovascular diseases (Mcmurray et al., 2012). With improvements in global economic levels, changes in human dietary structures, and poor lifestyle habits, HF has become a worldwide public health issue. A systematic review by Askoxylakis et al.