Shiki Fujino

Oct 9, 2024 | mdpi.com | Norikatsu Miyoshi |Shiki Fujino |Kengo Haruna |Soichiro Minami

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Feb 28, 2024 | iv.iiarjournals.org | Ryota Mori |Norikatsu Miyoshi |Shiki Fujino |Tsunekazu Mizushima

Key Words:Adipose derived stem cellanal sphincter injuryintestinal incontinenceARSdefecation functionIntestinal incontinence is a common condition defined as the uncontrolled passage of feces or gas for at least one month and has a negative impact on quality of life (1). Although the main causes of defecation problems have been age-related weakness of defecation-related muscle groups, the number of patients who develop the condition after surgery has increased.

Nov 23, 2023 | nature.com | Shiki Fujino |Norikatsu Miyoshi |Jun Koseki |Tsunekazu Mizushima

AbstractCirculating tumor cells (CTCs) play an important role in metastasis and recurrence. However, which cells comprise the complex tumor lineages in recurrence and are key in metastasis are unknown in colorectal cancer (CRC). CRC with high expression of POU5F1 has a poor prognosis with a high incidence of liver metastatic recurrence.

Feb 6, 2023 | nature.com | Shiki Fujino

AbstractApproximately 10% of patients with colorectal cancer with submucosal invasion have lymph node metastasis. Pathological risk factors for lymph node metastasis have varying sensitivities and specificities. To predict the risk of lymph node metastasis, the identification of new risk factors is vital. Tumor-infiltrating T cells have been reported to improve the prognosis of many solid tumors.