Shirley Wang

1 month ago | ascpt.onlinelibrary.wiley.com | Shirley Wang |Massimiliano Russo |Robert J Glynn |Marie Bradley

WHAT IS THE CURRENT KNOWLEDGE ON THIS TOPIC? Real-world evidence involving healthcare database studies is well established for making causal inferences in post-market drug safety studies and methods, data, and research infrastructure for evaluating effectiveness have advanced in recent years. WHAT QUESTION DID THIS STUDY ADDRESS?

2 months ago | onlinelibrary.wiley.com | Shirley Wang |Anton Pottegård

EDITORIAL Advancing Research Transparency and Reproducibility in Pharmacoepidemiology Shirley V. Wang,  Corresponding Author Shirley V. Wang Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Boston, Massachusetts, USA Department of Msedicine, Harvard Medical School, Boston, Massachusetts, USA Correspondence: Shirley V.

Jan 9, 2025 | acrjournals.onlinelibrary.wiley.com | Elvira D'Andrea MD |Shirley Wang

No abstract is available for this article. Supporting Information Filename Description art43103-sup-0001-Disclosureform.pdfPDF document, 192.7 KB Disclosure Form

Oct 23, 2024 | nature.com | Shirley Wang |Jordyn R. Ricard |Yaniv Yacoby

AbstractSuicide risk is highest immediately after psychiatric hospitalization, but the field lacks methods for identifying which patients are at greatest risk, and when. We built personalized models predicting suicidal thoughts after psychiatric hospital visits (N = 89 patients), using ecological momentary assessment (EMA; average EMA responses per participant = 311).

Sep 17, 2024 | ascpt.onlinelibrary.wiley.com | Janick Weberpals |Shirley Wang

Regulators increasingly rely on real-world evidence generated from routine-care health data to evaluate novel therapies. Particularly, external control arms are increasingly used to supplement and contextualize efficacy and safety claims of single arm clinical trials for rare disease therapies. However, there are a number of methodological issues that may affect the validity of results derived from such comparisons.