Shuai Fang

Sep 15, 2024 | biorxiv.org | Shuai Fang |Li Zhou |Geng Chen |Xiaoyu Wang

AbstractThe E3 ubiquitin (UB) ligase Parkin utilizes a Ring-Between-Ring (RBR) domain to mediate the transfer of UB to its substrates to regulate diverse cellular functions, including mitochondrial quality control, cell cycle progression, metabolism programming, and the establishment of synaptic functions. Mutations affecting the E3 ligase activity of Parkin are associated with cancer and Parkinson's disease (PD).

Oct 12, 2023 | mdpi.com | Zhiyuan Wang |Shuai Fang

2. Related WorksThe current STF methods are primarily categorized into three main approaches: weighted function-based, unmixing-based, and learning-based algorithms []. Weight function-based methods employ linear combinations of input image information to obtain refined pixel values.