Shuai He

Jan 2, 2025 | jci.org | Yanni Zeng |Chun-Ling Luo |Guo-Wang Lin |Fugui Li |Xiaomeng Bai |Josephine Mun-Yee Ko | +12 more

AbstractNasopharyngeal carcinoma (NPC) presents a substantial clinical challenge due to the limited understanding of its genetic underpinnings. Here we conduct the largest scale whole-exome sequencing association study of NPC to date, encompassing 6,969 NPC cases and 7,100 controls. We unveil 3 germline genetic variants linked to NPC susceptibility: a common rs2276868 in RPL14, a rare rs5361 in SELE, and a common rs1050462 in HLA-B.

Mar 11, 2024 | mdpi.com | Ke Han |Shuai He |Yue Stell Yu

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Sep 27, 2023 | onlinelibrary.wiley.com | Yixuan Huang |Shuai He |Sheng Yu |Hannah Johnson

Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202304119-sup-0001-SuppMat.pdf1.3 MB Supporting Information References 1, Chem. Soc. Rev. 2006, 35, 52. 2, , , Nat. Rev. Cancer 2012, 12, 170. 3, , , , Nature 2008, 453, 314. 4, Science 1997, 276, 75. 5, , , , , , , , , , , Nat. Commun. 2021, 12, 1670. 6, , , , , , , Nat. Commun. 2017, 8, 14684. 7, , , , , , , , , , , , , , , , , , , , Sci. Transl. Med.