Shunsuke Uchiyama

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Mosaic loss of chromosome Y characterizes late-onset rheumatoid arthritis and contrasting associations of polygenic risk score based on age at onset.

Sep 13, 2024 | medrxiv.org | Yuki Ishikawa |Katsunori Ikari |Suguru Honda |Shunsuke Uchiyama

S.U., Y.I., K.I., S.H., K.H., E.T., and C.T. have no conflicts of interest. Y.K. has research grants from Takeda Pharmaceuticals. T.G. received speaking fees from Asahi Kasei Pharma, Astellas, Boehringer-Ingelheim, Bristol-Myers Squibb, Chugai, Eisai, Eli Lily, Gilead Sciences, Ono Pharmaceuticals, Pfizer, and Tanabe Mitsubishi. G.G. declared competing interests, and patent application PCT/WO2019/079493 has been filed for the mosaic chromosomal alteration detection method used in this study.

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