Zhong-Wei Zhou

Nov 7, 2023 | frontiersin.org | Zhong-Wei Zhou |Simone Chiola |Xiaoqian Liu

1 IntroductionMicrocephaly in human is a developmental disorder that results in a reduction of head size such that head circumference is three standard deviations lower than the mean for a human of the same age and sex. A major cause of microcephaly is an impaired development of the brain (microencephaly) (Kaindl et al., 2010; Gilmore and Walsh, 2013; Alcantara and O'Driscoll, 2014; Jayaraman et al., 2018; Phan and Holland, 2021; Zaqout and Kaindl, 2022), which is the focus of this treatise.

Nov 6, 2023 | frontiersin.org | Charles R. Drew |Zhong-Wei Zhou |Ferdinando Di Cunto |Todd Schoborg

1 Introduction Microcephaly is a clinical condition where the occipito-frontal head circumference (OCF) of an individual is significantly smaller than the average head size of the population for a given sex and age (Lim and Golden, 2020).