Sinem Civriz Bozdag

May 15, 2023 | frontiersin.org | Xiao-Ping Xu |Mutlu Arat |Sinem Civriz Bozdag |Robert Chen

1. Introduction Perioperative allogeneic blood transfusion is often required in patients undergoing multilevel spinal fusion surgery, due to the complexity of the surgery and the high risk of intraoperative mass blood loss (1–3). Transfusion could solve the problems such as anemia and hypovolemia caused by bleeding profusely (4, 5). However, adverse blood transfusion reactions and lack of blood supply are still unavoidable.