Sishu Zhao

Mar 27, 2024 | onlinelibrary.wiley.com | Xiao Chen |Xia Chen |Yu Shi |Sishu Zhao

1 INTRODUCTION Chronic lymphocytic leukemia (CLL) is a neoplasm characterized by the monoclonal proliferation of mature B-cells within the peripheral blood (PB), bone marrow (BM), and secondary lymphoid tissues and is the most common type of leukemia in Western countries (Alaggio et al., 2023).