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2 months ago | 
digitalcommons.library.tmc.edu | Sairam Behera |Jonathan Belyeu |Xiao Chen |Luis F. Paulin
KeywordsHumans, Cardiovascular Diseases, Alleles, Lipoprotein(a), DNA Copy Number Variations, Genetic Predisposition to Disease, Polymorphism, Single Nucleotide, LPA, Copy number variation, Cardiovascular disease, Next Generation Sequencing, IlluminaAbstractThe abundance of Lp(a) protein holds significant implications for the risk of cardiovascular disease (CVD), which is directly impacted by the copy number (CN) of KIV-2, a 5.5 kbp sub-region.
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Jan 17, 2025 | 
nature.com | Chenqi Tang |Canlong Wang |Yue Ying |Zi Yin |Hongwei Ouyang |Xiao Chen
Correction to: Nature Communications https://doi.org/10.1038/s41467-024-53826-w, published online 1 November 2024In the original version of this manuscript. the Acknowledgements section did not mention the NSFC funding grant T2121004. The sentence “NSFC grants (82372376 to W.S., 82301766 to C.T.)” has been changed to “NSFC grants (T2121004 to H.O. and X.C., 82372376 to W.S., 82301766 to C.T.)”. This has been corrected in both the PDF and HTML versions of the Article.
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Dec 18, 2024 | 
mdpi.com | Xiao Chen
1. IntroductionIn precision instruments, geometric distribution error (GDE) [1] affects the accuracy and stability of assembled products. The analysis and processing method of GDE data, especially on how to effectively separate systematical error and random error, is an urgent problem in establishing a precision electromechanical product’s assembly contact surface GDE model and optimizing the assembly process [2].
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Dec 2, 2024 | 
mdpi.com | Hui Dong |Xiao Pan |Xiao Chen
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Nov 20, 2024 | 
onlinelibrary.wiley.com | Xiao Chen |Nanosystems Chinese Academy |Xiao Mei Peng |Chuanhui Wei
Conflict of Interest The authors declare no conflict of interest.
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Nov 19, 2024 | 
nature.com | Xiao Chen
AbstractThe concept and development of bone/cartilage organoids are rapidly gaining momentum, providing opportunities for both fundamental and translational research in bone biology. Bone/cartilage organoids, essentially miniature bone/cartilage tissues grown in vitro, enable the study of complex cellular interactions, biological processes, and disease pathology in a representative and controlled environment.
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Nov 18, 2024 | 
biorxiv.org | Lei Zhang |Yang Wang |Xiao Chen |Jie Hou
AbstractMotivation: With the advancement of deep learning, researchers have increasingly proposed computational methods based on deep learning techniques to predict protein function. However, many of these methods treat protein function prediction as a multi-label classification problem, often overlooking the long-tail distribution of functional labels (i.e., Gene Ontology Terms) in datasets.
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Oct 31, 2024 | 
nature.com | Chenqi Tang |Canlong Wang |Yue Ying |Zi Yin |Hongwei Ouyang |Xiao Chen
AbstractRotator cuff tendinopathy is the most common tendinopathy type with the worst prognosis. Conventional treatments often elicit heterogeneous drug responses due to the diversity of tendinopathy. Hence, this study attempted a classification of 126 diseased tendons into three distinct subtypes with opposite pathogenic mechanisms based on transcriptomic and clinical features. The hypoxic atrophic subtype with white appearance (Hw) exhibits downregulated neovascularization pathways.
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Oct 25, 2024 | 
mdpi.com | Xiao Chen |Zilong Li |Zhenyu Wang |jiayu Li
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Oct 22, 2024 | 
pubs.rsc.org | Ya Chen |Xin Gao |Zheng Zhen |Xiao Chen
The Construction of Multifunctional Solid Electrolytes Interlayers for Stabilizing Li6PS5Cl-based All-Solid-State Lithium Metal Batteries
The electrochemical performance of all-solid-state Li metal batteries (ASSLMBs) can be prominently consolidated by resolving the challenges triggered by the uncontrolled growth of Li dendrites throughout the solid electrolytes (SEs).
