Site Pitié-Salpêtrière

Oct 9, 2024 | link.springer.com | APHP Sorbonne Université |Site Pitié-Salpêtrière |Faculté de Médecine |Université Laval

AbstractDyspnea is associated with fear and intense suffering and is often assessed using visual analog scales (VAS) or numerical rating scales (NRS). However, the physiological correlates of such ratings are not well known. Using the voluntary breath-holding model of induced dyspnea, we studied healthy volunteers to investigate the temporal relationship between dyspnea, the neural drive to breathe assessed in terms of involuntary thoracoabdominal movements (ITMs) and neurovegetative responses.

Jul 16, 2024 | respiratory-research.biomedcentral.com | Site Pitié-Salpêtrière

This is a single-center phase 2 double-blind randomized controlled trial conducted in a 22-bed medical ICU within La Pitié-Salpêtrière University Hospital in Paris, France. The trial was approved by the Institutional Review Board (South Mediterranean III Comité de Protection des Personnes on December 5, 2019, no. 19.10.24.60836). All patients or relatives provided written informed consent. The protocol was declared on the ClinicalTrial.gov database (no.

Oct 31, 2023 | ccforum.biomedcentral.com | Site Pitié-Salpêtrière

In the recent ESICM guidelines on Acute Respiratory Distress Syndrome [1], the group of experts was “unable to make a recommendation for or against routine PEEP titration with higher PEEP/FiO2 strategy versus a lower PEEP/FiO2 strategy.” Also, the committee was “unable to make a recommendation for or against PEEP titration guided by respiratory mechanics, compared to PEEP titration principally on PEEP/FiO2 strategy.” These recommendations are undoubtedly sound from a methodological...