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Feb 2, 2024 | 
science.org | Zi-Xian Liu |Skye Montoya |Shou Qiu
Research ArticleCláudia Brito https://orcid.org/0000-0002-2320-7747, Marina Serna https://orcid.org/0000-0002-6827-496X, [...] , Pablo Guerra https://orcid.org/0000-0002-0154-3862, Oscar Llorca https://orcid.org/0000-0001-5705-0699 [email protected], and Thomas Surrey https://orcid.org/0000-0001-9082-1870 [email protected]+2 authors fewerAuthors Info & AffiliationsAbstractMicrotubules are essential for intracellular organization and chromosome segregation.
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Feb 2, 2024 | 
sciencemag.org | Zi-Xian Liu |Skye Montoya |Shou Qiu
1E. Nogales, M. Whittaker, R. A. Milligan, K. H. Downing, High-resolution model of the microtubule. Cell96, 79–88 (1999). 2E. Nogales, R. Zhang, Visualizing microtubule structural transitions and interactions with associated proteins. Curr. Opin. Struct. Biol.37, 90–96 (2016). 3S. W. Manka, C. A. Moores, Microtubule structure by cryo-EM: Snapshots of dynamic instability. Essays Biochem.62, 737–751 (2018). 4E. M. Mandelkow, R. Schultheiss, R. Rapp, M. Müller, E.
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Feb 1, 2024 | 
science.org | Zi-Xian Liu |Skye Montoya |Shou Qiu
Expanded Genomics ServicesAzenta Life Sciences has expanded services to the United Kingdom, opening a new lab in Oxford as its GENEWIZ Multiomics and Synthesis Solutions site for the region. The site will feature a new state-of-the-art genomics lab scheduled to open in March 2024. Drawing upon the experience of scientists at the former Oxford Genomics Centre (OGC), the new Oxford Genomics Lab will provide genomics services from GENEWIZ to support a wide range of project needs from its customers.
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Feb 1, 2024 | 
science.org | Zi-Xian Liu |Skye Montoya |Shou Qiu |Miao Wang
Research ArticleORGANIC CHEMISTRYMiao Wang https://orcid.org/0009-0005-1070-6140, Yahao Huang https://orcid.org/0009-0005-8872-2845, and Peng Hu https://orcid.org/0000-0001-7864-3514 [email protected] Info & AffiliationsEditor’s summaryBorylation has emerged in the past two decades as a - means of substituting the otherwise unreactive carbon–hydrogen bonds abundant in many feedstock chemicals. Nonetheless, site selectivity in alkyl chains remains a challenge. Wang et al.
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Feb 1, 2024 | 
science.org | Zi-Xian Liu |Skye Montoya |Shou Qiu |Yvonne M. Buckley
Both extinctions and introductions of large mammalian herbivores (>45 kg) affect biodiversity and ecosystem function. An important question is whether the origin of herbivorous megafauna predicts impacts on an ecosystem that are specific to introduced species in general, more severe than those of native species, or both.
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Feb 1, 2024 | 
science.org | Zi-Xian Liu |Skye Montoya |Shou Qiu |R. Eric Davis
PerspectiveMedicineRedirecting targeted proteins for degradation can overcome acquired drug resistanceR. Eric Davis [email protected] and Jason R. WestinAuthors Info & AffiliationsAbstractAmino acid sequence determines a protein’s behavior, including drug susceptibility and its interacting proteins. Genomic instability enables cancer development but can also produce variants of proteins that resist targeted therapy, sometimes by changing the protein’s function and protein partners.
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Feb 1, 2024 | 
science.org | Zi-Xian Liu |Skye Montoya |Shou Qiu |Chris T. Darimont
Chris T. Darimont [email protected] and Paul C. PaquetAuthors Info & AffiliationsGet full access to this articleView all available purchase options and get full access to this article. References and Notes1M. Morton, “$10M spent on B.C. wolf cull, FOI documents reveal alongside details of shootings,” Canadian Broadcasting Corporation News (2023). 2R. Serrouya et al., Proc. Natl. Acad. Sci. U.S.A. 116, 6181 (2019). 3L. E. Harding et al., Biodivers. Conserv. 29, 3051 (2020). 4S. Frey, D. Tejero, K. Baillie-David, A.
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Feb 1, 2024 | 
science.org | Zi-Xian Liu |Skye Montoya |Shou Qiu |Ekeoma Uzogara
Linguistics The evolution of sign languages globallyEkeoma UzogaraSchools for deaf communities have helped codify and spread independent sign language families in Europe and Asia. PHOTO: ANADOLU AGENCY VIA GETTY IMAGESOpen in viewerLanguages constantly evolve, and advances in computational phylogenetics allow for the detection of relationships among different spoken language groups on the basis of vocabulary and grammatical properties.
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Feb 1, 2024 | 
science.org | Zi-Xian Liu |Skye Montoya |Shou Qiu |Victor Ray
eLetters is a forum for ongoing peer review. eLetters are not edited, proofread, or indexed, but they are screened. eLetters should provide substantive and scholarly commentary on the article. Embedded figures cannot be submitted, and we discourage the use of figures within eLetters in general. If a figure is essential, please include a link to the figure within the text of the eLetter. Please read our Terms of Service before submitting an eLetter.
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Feb 1, 2024 | 
science.org | Zi-Xian Liu |Skye Montoya |Shou Qiu |Bianca Lopez
Agroecology Landscape effects on insect pestsBianca LopezIn Brazil, farms interspersed with natural vegetation harboring wild predators suffer less from whitefly depredation. PHOTO: IMAGEBROKER.COM GMBH & CO. KG/ALAMY STOCK PHOTOOpen in viewerInsects play important roles on farms, both as pests that damage crops and as natural enemies (predators and parasitoids) that control their populations.
