Songlei Liu

Oct 13, 2024 | biorxiv.org | Songlei Liu |George M Church |Craig Hunter |Andrei Shubin

AbstractThe prevalence and significance of intercellular mRNA transport remains unknown. Direct detection of mRNA transfer between cells within an organism is challenging due to technical limitations associated with transgene encoded molecular labels and cell sorting techniques. In this study we analyzed human-to-mouse xenograft single-cell RNA sequencing data to identify mouse transcripts in recovered human cells.