Spencer Gordon

Sep 27, 2024 | biorxiv.org | Spencer Gordon |Alyssa Rodriguez |Yajie Gu |Kevin Corbett

AbstractDuring meiosis, the parental chromosomes are drawn together to enable exchange of genetic information. Chromosomes are aligned through the assembly of a conserved interface, the synaptonemal complex, composed of a central region that forms between two parallel chromosomal backbones called axes. Here we identify the axis-central region interface in C. elegans, containing a conserved positive patch on the axis component HIM-3 and the C-terminus of the central region protein SYP-5.