Srivastava Akanksha

Nov 24, 2024 | biorxiv.org | Gabriela Rodriguez |Gabriela Rodríguez |Agin Ravindran |Srivastava Akanksha |Favour Oyelami

AbstractGene expression programs underpin the development of shared phenotypes, yet the importance of transcript complexity in shaping mammalian evolution remains unclear. Here we present a comprehensive long-read direct RNA sequencing atlas of full-length transcripts and their m6A modifications across six tissues (hippocampus, frontal cortex, cerebellum, testes, skeletal muscle, and liver) in five mammals (human, mouse, rat, dog, and cow) and a non-mammalian out-group (chicken).