Stefano Confalonieri

May 17, 2024 | onlinelibrary.wiley.com | Stefano Confalonieri |Rosa Pennisi |Flavia Martino |Bronislava Matoskova

1 Introduction The ability of tumors to adapt their metabolism to match specific needs is a recognized hallmark of cancer, crucial in shaping tumor evolution and disease progression.[1] Metabolic plasticity is exemplified by aerobic glycolysis, commonly referred to as the Warburg effect.[2] This phenomenon involves the avid uptake of glucose by cancer cells and its conversion to lactate even in the presence of oxygen.[3] Traditionally, the Warburg effect was viewed as a strategy adopted by...