Articles

  • 4 weeks ago | bigthink.com | Stephen Johnson

    A weekly newsletter featuring the biggest ideas from the smartest people Imagine lounging in a hammock on a sunny beach, palm trees swaying in the breeze, the bright turquoise of the sea barely dimmed by your sunglasses. You glance up the beach, then down the beach: not a soul in sight. It’s only the first day of your holiday and your whole body feels so relaxed, you could dissolve into the sand and be swept out to sea. You take a lazy sip of your pina colada and take it all in.

  • Dec 31, 2024 | bigthink.com | Stephen Johnson

    A weekly newsletter featuring the biggest ideas from the smartest people The Earth is under attack — not by humanity or rampaging aliens, but by the Universe itself. Vast cosmic forces break apart hydrogen atoms and fling their components across the cosmos at nearly the speed of light. Some of these interstellar projectiles smash into the Earth’s atmosphere, allowing sensitive detectors to unravel their secrets.

  • Oct 13, 2024 | biorxiv.org | Stephen Johnson |Michael Beard |Siena M Centofanti |Gustavo Bracho

    AbstractSecreted non-structural protein 1 (sNS1) is an important orthoflavivirus pathogenic factor that can induce vascular leakage; a key symptom of severe dengue disease. Given the role of sNS1 in dengue pathogenesis, defining the molecular mechanisms of NS1 secretion may contribute towards development of NS1-targeting antiviral therapies. To this end, we performed a customised membrane-trafficking siRNA screen to identify human host factors involved in NS1 secretion.

  • Sep 2, 2024 | techradar.com | Stephen Johnson

    (Image credit: Shutterstock)Today’s society is more dependent on technology than ever before. Virtually every aspect of our daily lives is intertwined with IT infrastructure, from the way we communicate and work to how we access essential services like banking and healthcare. This deep integration means that even the smallest error in a system can have profound consequences, affecting millions of people and causing significant disruptions.

  • Aug 17, 2024 | bigthink.com | Stephen Johnson

    A weekly newsletter featuring the biggest ideas from the smartest people If physics ruled the 20th century, the 21st is shaping up to be the century of biology. The past two decades have brought us the completion of the Human Genome Project, the advent of CRISPR technology, the development of mRNA drugs, advances in personalized medicine and stem-cell therapies, and, more recently, AI advances that promise to accelerate our understanding of diseases and drug discovery.

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