Stevie Hamilton

Mar 7, 2024 | nature.com | Daniel M. Virga |Stevie Hamilton |Abigail Daisy Morgan |Victoria Hewitt |D. Grahame Hardie |Julien Prudent | +2 more

AbstractNeuronal mitochondria play important roles beyond ATP generation, including Ca2+ uptake, and therefore have instructive roles in synaptic function and neuronal response properties. Mitochondrial morphology differs significantly between the axon and dendrites of a given neuronal subtype, but in CA1 pyramidal neurons (PNs) of the hippocampus, mitochondria within the dendritic arbor also display a remarkable degree of subcellular, layer-specific compartmentalization.