
Sujuan Yang
Articles
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Nov 6, 2024 |
digitalcommons.library.tmc.edu | Krishnan K Mahadevan |Kathleen M. McAndrews |Valerie S LeBleu |Sujuan Yang
AbstractThe KRASG12D mutation is present in nearly half of pancreatic adenocarcinomas (PDAC). We investigated the effects of inhibiting the KRASG12D mutant protein with MRTX1133, a non-covalent small molecule inhibitor of KRASG12D, on early and advanced PDAC and its influence on the tumor microenvironment.
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Aug 24, 2023 |
cell.com | Krishnan K Mahadevan |Kathleen M. McAndrews |Valerie S LeBleu |Sujuan Yang
The KRASG12D mutation is present in nearly half of pancreatic adenocarcinomas (PDAC). We investigated the effects of inhibiting the KRASG12D mutant protein with MRTX1133, a non-covalent small molecule inhibitor of KRASG12D, on early and advanced PDAC and its influence on the tumor microenvironment.
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