Susan Neuhausen

Nov 29, 2023 | nature.com | Beth Karlan |Olufunmilayo I. Olopade |Christian F. Singer |Susan Neuhausen |Charis Eng |Steven A. Narod

AbstractRisk-reducing mastectomy (RRM) is offered to women with a BRCA1 or BRCA2 pathogenic variant, however, there are limited data on the impact on breast cancer mortality. Participants were identified from a registry of women with BRCA1/2 pathogenic variants. We used a pseudo-randomised trial design and matched one woman with a RRM to one woman without a RRM on year of birth, gene, and country.