Sven Hildebrand

Aug 26, 2024 | biorxiv.org | Sven Hildebrand |Johannes Franz |Hanna Hoogen |Michael Capalbo

AbstractNon-invasive imaging techniques, such as ultra-high field fMRI, are intricately connected to the underlying vasculature and are approaching ever higher resolutions. For the analysis of fMRI signals over cortical depth at such high resolutions, microvascular differences might have to be taken into account. Therefore, a better understanding of the laminar distribution and interareal differences in the cortical vasculature is becoming more important.

Mar 27, 2024 | nature.com | Nikita Vladimirov |Fabian Voigt |Sven Hildebrand |Dominik Groos |José María Mateos |Philipp Bethge | +5 more

AbstractIn 2015, we launched the mesoSPIM initiative, an open-source project for making light-sheet microscopy of large cleared tissues more accessible. Meanwhile, the demand for imaging larger samples at higher speed and resolution has increased, requiring major improvements in the capabilities of such microscopes.

Feb 13, 2023 | nature.com | Anna Schueth |Sven Hildebrand |Iryna V. Samarska

Human brain samplesHuman occipital lobe samples were taken from 3 human body donors (donor 1: male, 98 years; donor 2: female, 101 years; donor 3: female 90 years; no known neuropathological diseases, respectively) of the body donation programme of the Department of Anatomy and Embryology, Maastricht University (UM). Tissue from donors 2 and 3 were used for the shrinkage evaluation (Supplementary Fig. 3).