Tali Shalit

Aug 25, 2024 | nature.com | Gal Aviel |Jacob Elkahal |Kfir Baruch Umansky |David Kain |Tali Shalit |Shoval Miyara | +2 more

AbstractMyocardial injury may ultimately lead to adverse ventricular remodeling and development of heart failure (HF), which is a major cause of morbidity and mortality worldwide. Given the slow pace and substantial costs of developing new therapeutics, drug repurposing is an attractive alternative. Studies of many organs, including the heart, highlight the importance of the immune system in modulating injury and repair outcomes.

Feb 7, 2024 | nature.com | Tali Shalit |Ivan Milenković

AbstractDespite being the second most common neurodegenerative disorder, little is known about Parkinson’s disease (PD) pathogenesis. A number of genetic factors predispose towards PD, among them mutations in GBA1, which encodes the lysosomal enzyme acid-β-glucosidase. We now perform non-targeted, mass spectrometry based quantitative proteomics on five brain regions from PD patients with a GBA1 mutation (PD-GBA) and compare to age- and sex-matched idiopathic PD patients (IPD) and controls.

Dec 10, 2023 | onlinelibrary.wiley.com | Shani Blumenreich |Tali Shalit |Doreen Padan Ben-Yashar |Meital Kupervaser

CONFLICT OF INTEREST STATEMENT The authors declare that they have no conflict of interest. Supporting Information Filename Description jnc16024-sup-0001-Supinfo.docxWord 2007 document , 2 MB Data S1. jnc16024-sup-0002-Table2.xlsxExcel 2007 spreadsheet , 144.3 KB Table 3. jnc16024-sup-0003-Table3.xlsxExcel 2007 spreadsheet , 770.1 KB Table 3. jnc16024-sup-0004-Table4.xlsxExcel 2007 spreadsheet , 44 KB Table 4. REFERENCES , & (2013).