Tasneem Cheytan

Nov 14, 2024 | cell.com | Zhiyi Chen |Alex Inague |Kamini Kaushal |Gholamreza Fazeli |Tasneem Cheytan |Florencio Porto Freitas | +26 more

Keywordsferroptosiscancer metabolismseleniumselenocysteine metabolismcell deathneuroblastomaIntroductionFerroptosis is a non-apoptotic form of cell death characterized by the iron-dependent accumulation of phospholipid hydroperoxides, ultimately leading to membrane rupture and cell death.1 Due to its association with various pathological conditions, including cancer, neurodegeneration, and tissue damage,2 the mechanisms regulating ferroptosis have garnered increasing interest.