Tavia E. Evans

May 13, 2024 | digitalcommons.library.tmc.edu | Maria J. Knol |Raymond Poot |Tavia E. Evans |Claudia L. Satizabal

AbstractThe size of the human head is highly heritable, but genetic drivers of its variation within the general population remain unmapped. We perform a genome-wide association study on head size (N = 80,890) and identify 67 genetic loci, of which 50 are novel. Neuroimaging studies show that 17 variants affect specific brain areas, but most have widespread effects. Gene set enrichment is observed for various cancers and the p53, Wnt, and ErbB signaling pathways.

Apr 17, 2023 | nature.com | Marie-Gabrielle Duperron |Maria J. Knol |Quentin Le Grand |Tavia E. Evans |Ami Tsuchida |Gennady V Roshchupkin | +35 more

AbstractPerivascular space (PVS) burden is an emerging, poorly understood, magnetic resonance imaging marker of cerebral small vessel disease, a leading cause of stroke and dementia. Genome-wide association studies in up to 40,095 participants (18 population-based cohorts, 66.3 ± 8.6 yr, 96.9% European ancestry) revealed 24 genome-wide significant PVS risk loci, mainly in the white matter.

Mar 18, 2023 | stlamerican.com | Tavia E. Evans

When St. Louis’ Black population called for another “colored paper” to serve St. Louis 85 years ago, the city’s most prominent lawyers, teachers and businessmen stepped up to offer their support and pocket-books. Until then, the St. Louis Argus, founded in 1912, was the main media eyes and ears of the Black community.