-
1 month ago | 
obgyn.onlinelibrary.wiley.com | Kimia Ghannad-Zadeh |Temerty Faculty |Patrick Shannon |Rebekah Jobling
What's already known about this topic? ◦ Aberrant expression of KIDINS220 has been associated postnatally with neurodevelopment abnormalities and SINO syndrome. ◦ Most individuals with SINO syndrome present postnatally with macrocephaly and ventriculomegaly. Prenatal presentation and neuropathological findings are rarely reported. What does this study add?
-
2 months ago | 
jamanetwork.com | Temerty Faculty |Matthias Büttner |David J. Goldstein |Aaron R. Hansen
Importance
Generic health utility instruments lack the discriminative ability to differentiate among health states in patients after head and neck cancer treatment. Objective
To develop, validate, and valuate a head and neck cancer−specific health utility measure. Design, Setting, and Participants
This psychometric study comprised 2 phases to develop and validate a health utility instrument. The first phase, development and validation, occurred from January 2021 to August 2022.
-
Mar 3, 2025 | 
cmaj.ca | Shreya Jha |Temerty Faculty
As a composer, I have channelled emotions into art for as long as I can remember. When death was still only an abstract concept to me, I approached it with tentative curiosity. I allowed myself to feel hurt and heartbreak, even dark emptiness. I wrote, rewrote, and discarded, wondering if there was any beauty within the darkness of death. A month into my clerkship year, my friend passed away suddenly. She was 22 years old.
-
Jan 24, 2025 | 
onlinelibrary.wiley.com | Aditya Gupta |Temerty Faculty |Tong Wang
We read with interest the work by Rodríguez-Cerdeira, Pinto-Almazán and colleagues reviewing the epidemiology and resistance profile of Nakaseomyces glabratus (formerly Candida glabrata) in Europe.1 While current literature does not indicate that N. glabratus exhibits a similar degree of outbreak potential as C. auris,2 increased efforts in surveillance and resistance testing are warranted in view of its multi-drug resistance propensity.
-
Jan 16, 2025 | 
link.springer.com | Christopher J. D |Temerty Faculty
AbstractSome prior studies have found that patients treated by female physicians may experience better outcomes, as well as lower healthcare costs than those treated by male physicians. Physician–patient sex concordance may also contribute to better patient outcomes. However, other studies have not identified a significant difference. There is a paucity of pooled evidence examining the association of physician sex with clinical outcomes.
-
Jan 14, 2025 | 
journals.plos.org | Subin Park |Temerty Faculty |Anton Marinov |Hance Clarke
DiscussionThis study examined the safety profile of HBOT in a cohort of patients with a history of prior seizures. Over the course of 634 HBOT sessions among 22 patients, only one seizure was recorded, yielding an incidence of one in 634 treatments. In the literature, there is considerable variability in the incidence of seizure during HBOT, ranging from 0.25 in 10,000 to 6 per 10,000 [4–13].
-
Jan 14, 2025 | 
journals.plos.org | Aditya Gupta |Temerty Faculty |Vasiliki Economopoulos |Schulich Scholl
Materials and methodsThe All of Us research program, which aims to provide diverse and inclusive health data was accessed for this work. All analyses were performed using the registered tier dataset version 7 available within the All of Us research program, which includes data collected from US participants between the summer of 2017 and July 1, 2022.
-
Jan 13, 2025 | 
onlinelibrary.wiley.com | Aron A. Shoara |Temerty Faculty |Kanwal Singh |Development Canada
ADAMTS13 a disintegrin and metalloproteinase with a thrombospondin type 1 motif member 13 BCA bicinchoninic acid BLI biolayer interferometry CF clot formation CFT clot formation time CT clotting time DCR damage control resuscitation DLS dynamic light scattering DSC differential scanning calorimetry ELISA enzyme-linked immunosorbent assay FDP freeze-dried plasma FFP fresh frozen plasma GP glycoprotein HSA human serum albumin HDL high density lipoprotein HEPES 4-(2-hydroxyethyl)-1-piperazine...
-
Jan 13, 2025 | 
onlinelibrary.wiley.com | Eric Mcmullen |Temerty Faculty |Parsa Abdi |Labrador Canada
Letter to the Editor Pathogenesis of paradoxical alopecia areata during dupilumab therapy: What is known and unknown Eric McMullen, Corresponding Author Eric McMullen Division of Dermatology, Department of Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada Search for more papers by this authorParsa Abdi, Parsa Abdi Faculty of Medicine, Memorial University, St. Johns, Newfoundland and Labrador, Canada Search for more papers by this authorIryna Savinova,...
-
Jan 11, 2025 | 
qualitysafety.bmj.com | Maitreya Coffey |Kelly Smith |Temerty Faculty
Healthcare quality improvement Leadership Quality improvement In their article in this issue of BMJ Quality and Safety, ‘We listened and depended on and supported each other’, Ginsburg et al examine how leaders shaped the site-level experience in a quality improvement collaborative aimed at improving safety in long-term elder care.1 They performed a secondary thematic analysis of an existing mixed-methods data set generated from over 150 leaders and staff at 31 sites, where the qualitative...
