Thomas Bieber

Aug 23, 2024 | onlinelibrary.wiley.com | Thomas Bieber |Christine Kühne-Center

Atopic dermatitis (AD) is a highly heterogeneous phenotype with a wide spectrum of ages of onset while a subgroup of AD exhibit a substantial risk to develop IgE-mediated sensitization and further atopic comorbidities, that is, the so-called atopic march. Besides the complex genetic background, the potential role of the microbiome has been highlighted in the last decade with a focus on Staphylococcus aureus (S. aureus) assumed to be the ‘bad guys’ in the context of the reported dysbiosis in AD.

Aug 21, 2023 | nature.com | Thomas Bieber

Correction to: Nature Reviews Drug Discovery https://doi.org/10.1038/s41573-023-00735-0, published online 13 July 2023. In the version of the article initially published, the name of the drug rezpegaldesleukin was misspelt in Fig. 1, Tables 1 and 2, and the main text. The name of the drug roflumilast was also misspelt in Fig. 1. The errors have been corrected in the HTML and PDF versions of the article. About this articleBieber, T.

Aug 1, 2023 | nature.com | Pavel Kolkhir |Thomas Bieber |Emma Guttman-Yassky |Martin Metz |Harald Renz

AbstractOver the past two decades, significant progress in understanding of the pathogenesis of type 2 chronic inflammatory diseases has enabled the identification of compounds for more than 20 novel targets, which are approved or at various stages of development, finally facilitating a more targeted approach for the treatment of these disorders.

Jul 13, 2023 | nature.com | Thomas Bieber

AbstractProgress in understanding of the mechanisms underlying chronic inflammatory skin disorders, such as atopic dermatitis and psoriasis vulgaris, has led to new treatment options with the primary goal of alleviating symptoms. In addition, this knowledge has the potential to inform on new strategies aimed at inducing deep and therapy-free remission, that is, disease modification, potentially impacting on associated comorbidities.

Jun 15, 2023 | onlinelibrary.wiley.com | Andreas Wollenberg |Jacob P. Thyssen |Thomas Bieber |Gary C Chan

SHORT REPORT This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi:10.1111/jdv.19255.