Thomas Ernst Dorner

Sep 27, 2024 | science.org | Georg Schett |Thomas Ernst Dorner |Erika Gebel Berg

Our bodies are in a constant balancing act known as homeostasis. The ringleader behind all this? Autophagy, an essential lysosome-mediated degradation pathway that maintains cellular viability and death in response to various intra- and extra-cellular stress. It determines whether we remain healthy or succumb to diseases, such as cancer, Parkinson’s, and diabetes, and scientists have recently made headway in elucidating its pathways. Autophagy appears to be a double-edged sword.

Sep 20, 2024 | mdpi.com | Martin Mayer |Thomas Ernst Dorner |Selam Woldemariam |Christoph Gisinger

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.

Nov 6, 2023 | ard.bmj.com | Thomas Ernst Dorner |Martin Kaul |Antónia Szántó |Jui-Cheng Tseng

Introduction Primary Sjögren’s syndrome (SjS) is an autoimmune disorder characterised by lymphocytic infiltration of exocrine glands including significant loss of secretory function.1 2 Clinical symptoms commonly include oral and ocular dryness, fatigue and joint pain.2 3 Prevalence rates, which can vary depending on the classification criteria used, are estimated to be 0.01% to 2.7% globally, with a higher prevalence reported in females compared with males.2 4 5 Approximately 30%–40% of the...

Jul 13, 2023 | ard.bmj.com | Martin Aringer |Karen H Costenbader |Nicolai Leuchten |Thomas Ernst Dorner

http://orcid.org/0000-0003-4471-8375Martin Aringer1, Karen Costenbader2, Nicolai Leuchten1, http://orcid.org/0000-0002-6478-7725Thomas Dörner3, http://orcid.org/0000-0003-0591-2976Sindhu R Johnson4 1 Division of Rheumatology, Department of Medicine III, University Medical Center and Faculty of Medicine Carl Gustav Carus at the TU Dresden, Dresden, Germany 2 Division of Rheumatology, Immunology, and Allergy, Department of Medicine, Brigham and Womens Hospital, Harvard Medical School, Boston,...