Thomas Wälchli

Jul 10, 2024 | nature.com | Thomas Wälchli |Shigeki Takada |Hubert Rehrauer |Anuroopa Dinesh |Jeroen Bisschop |Fiona Farnhammer | +11 more

AbstractA broad range of brain pathologies critically relies on the vasculature, and cerebrovascular disease is a leading cause of death worldwide. However, the cellular and molecular architecture of the human brain vasculature remains incompletely understood1.

Oct 5, 2023 | dialnet.unirioja.es | Jason Charish |Hidekiyo Harada |Xiaoyan Chen |Thomas Wälchli

The Dyslexia-associated gene KIAA0319L is involved in neuronal migration in the developing chick visual systemAutores: Jason Charish, Hidekiyo Harada, Xiaoyan Chen, Thomas Wälchli, Cathy L. Barr, Philippe P. MonnierLocalización: International journal of developmental biology, ISSN 0214-6282, Vol. 67, Nº. 2, 2023, págs. 49-56Idioma: inglésEnlacesTexto completoResumenThe gene KIAA0319-Like (KIAA0319L) is thought to confer susceptibility for developmental dyslexia.

Mar 20, 2023 | nature.com | Jeroen Bisschop |Peter Carmeliet |Katrien De Bock |Thomas Wälchli

AbstractThe CNS critically relies on the formation and proper function of its vasculature during development, adult homeostasis and disease. Angiogenesis — the formation of new blood vessels — is highly active during brain development, enters almost complete quiescence in the healthy adult brain and is reactivated in vascular-dependent brain pathologies such as brain vascular malformations and brain tumours.