Tiffany J. Callahan

Aug 21, 2024 | nature.com | Emanuele Cavalleri |Jessica Gliozzo |Tiffany J. Callahan |Peter Robinson |Elena Casiraghi

AbstractThe “RNA world” represents a novel frontier for the study of fundamental biological processes and human diseases and is paving the way for the development of new drugs tailored to each patient’s biomolecular characteristics.

Apr 10, 2024 | nature.com | Tiffany J. Callahan |Sanya B. Taneja |Elena Casiraghi |Jonathan Silverstein |Charles Tapley Hoyt |Deepak R. Unni | +7 more

AbstractTranslational research requires data at multiple scales of biological organization. Advancements in sequencing and multi-omics technologies have increased the availability of these data, but researchers face significant integration challenges. Knowledge graphs (KGs) are used to model complex phenomena, and methods exist to construct them automatically. However, tackling complex biomedical integration problems requires flexibility in the way knowledge is modeled.