Timothy S. Chisholm

Dec 20, 2023 | pubs.rsc.org | Timothy S. Chisholm |Lensfield Road |Christopher A Hunter

A closer look at amyloid ligands, and what they tell us about protein aggregates† The accumulation of amyloid fibrils is characteristic of neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease. Detecting these fibrils with fluorescent or radiolabelled ligands is one strategy for diagnosing and better understanding these diseases. A vast number of amyloid-binding ligands have been reported in the literature as a result.