Tomas Gonzales

Jun 4, 2024 | nature.com | Andrew Perry |Eric Farber-Eger |Tomas Gonzales |Venkatesh L. Murthy |Laura A. Colangelo |Keenan A. Walker | +8 more

AbstractDespite the wide effects of cardiorespiratory fitness (CRF) on metabolic, cardiovascular, pulmonary and neurological health, challenges in the feasibility and reproducibility of CRF measurements have impeded its use for clinical decision-making. Here we link proteomic profiles to CRF in 14,145 individuals across four international cohorts with diverse CRF ascertainment methods to establish, validate and characterize a proteomic CRF score.