
Articles
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1 month ago |
arxiv.org | Mathias Sonnleitner |Tomasz Szczepanski |Tomasz Szczepański
arXiv:2505.10929 (math) View PDF HTML (experimental) Comments: Subjects: Metric Geometry (math.MG); Numerical Analysis (math.NA) MSC classes: 52B55, 52C17 (Primary) 52A23, 52C45 (Secondary) Cite as: arXiv:2505.10929 [math.MG] (or arXiv:2505.10929v1 [math.MG] for this version) https://doi.org/10.48550/arXiv.2505.10929 Submission history From: Mathias Sonnleitner [ view email] [v1] Fri, 16 May 2025 07:07:56 UTC (23 KB) Bibliographic Tools Bibliographic Explorer Toggle Bibliographic Explorer ()...
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Aug 27, 2024 |
nature.com | Agata Pastorczak |Zuzanna Urbanska |Borys Styka |Zuzanna Nowicka |Tomasz Szczepanski |Tomasz Szczepański | +4 more
AbstractChromothripsis (cth) is a form of genomic instability leading to massive de novo structural chromosome rearrangements in a one-time catastrophic event. It can cause cancer-promoting alterations, such as loss of sequences for tumor-suppressor genes, formation of oncogenic fusions, and oncogene amplifications. We investigated the genetic background and clinical significance of cth in childhood T-cell acute lymphoblastic leukemia (T-ALL) patients.
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