Tres Cookenham

Feb 14, 2024 | nature.com | In-Jeong Kim |Michael Tighe |Vincent Dussupt |Shelly J. Krebs |Kelsey L. Travis |Tres Cookenham | +7 more

AbstractZika virus (ZIKV) is a significant threat to pregnant women and their fetuses as it can cause severe birth defects and congenital neurodevelopmental disorders, referred to as congenital Zika syndrome (CZS). Thus, a safe and effective ZIKV vaccine for pregnant women to prevent in utero ZIKV infection is of utmost importance. Murine models of ZIKV infection are limited by the fact that immunocompetent mice are resistant to ZIKV infection.