Trilby Langton

Apr 9, 2024 | adc.bmj.com | Jo Taylor |Ruth Hall |Trilby Langton |Lorna K Fraser

DiscussionThis systematic review found that there has been a twofold to threefold increase in the number of referrals to specialist paediatric gender/endocrinology services over time across countries. An increase in the ratio of birth-registered females to males was also observed.

Apr 9, 2024 | adc.bmj.com | Jo Taylor |Alex Mitchell |Ruth E. Hall |Trilby Langton

DiscussionThis systematic review identified 53 studies reporting outcomes for feminising/masculinising hormones for adolescents experiencing gender dysphoria/incongruence. Only 6 of the 12 cohort studies were rated as high or moderate quality.34 37–39 54 76There was evidence from multiple studies that exogenous hormones increase hormone levels and to varying degrees induce pubertal development, with potential differences depending on birth-registered sex and timing of treatment.

Apr 9, 2024 | adc.bmj.com | Shaw RM |Jo Taylor |Ruth E. Hall |Trilby Langton

DiscussionThis review of 23 studies from nine countries found that children and adolescents referred to or assessed in specialist paediatric gender and endocrinology services leave the care pathway at all stages following referral for multiple reasons.

Apr 9, 2024 | adc.bmj.com | Ruth Hall |Jo Taylor |Claire Heathcote |Trilby Langton

DiscussionThis survey found some similarities across paediatric gender services in eight countries and also some key points of divergence in the management of co-occurring conditions, prepubertal care and criteria for accessing medical interventions. We also found a paucity of in-house psychosocial interventions available and limited routine follow-up data collection across services.