Tuomas Hämälä

Jun 24, 2024 | nature.com | Tuomas Hämälä |Christopher Moore |Marcus Koch

AbstractPolyploidy, the result of whole-genome duplication (WGD), is a major driver of eukaryote evolution. Yet WGDs are hugely disruptive mutations, and we still lack a clear understanding of their fitness consequences. Here, we study whether WGDs result in greater diversity of genomic structural variants (SVs) and how they influence evolutionary dynamics in a plant genus, Cochlearia (Brassicaceae).

Sep 28, 2023 | biorxiv.org | Sian Bray |Tuomas Hämälä |Min Zhou |Silvia Busoms

AbstractWhole genome duplication (WGD) brings challenges to key processes like meiosis, but nevertheless is associated with diversification in all kingdoms. How is WGD tolerated, and what processes commonly evolve to stabilize the new polyploid lineage? Here we study this in Cochlearia spp., which have experienced multiple rounds of WGD in the last 300,000 years.