Tyler Menichiello

1 week ago | bioprocessonline.com | Tyler Menichiello |Kihong Kim |Samsung BioLogics

FOCUS ON DOWNSTREAM MANUFACTURINGThis summary features key takeaways from the Bioprocess Online Live event, "Challenges And Considerations For Purifying Multispecific Molecules."Polishing Strategy For Removing Impurities In bsAb PurificationExamine a Bispecific antibodies (bsAbs) polishing strategy that utilizes a multimodal chromatography media to address the unique challenges presented by bsAb downstream processing.

4 weeks ago | bioprocessonline.com | Tyler Menichiello

By Tyler Menichiello, contributing editor In case you missed it, this month’s Bioprocess Online Live was all about the challenges and special considerations for purifying multispecifics — molecules engineered to engage two or more distinct targets (e.g., bispecific or trispecific antibodies). I was joined by two expert panelists: Mark Fitchmun, president and CEO of Somatek, and Jian Ren, Ph.D., a principal scientist in AbbVie’s manufacturing science and technology (MSAT) bioresearch center.

1 month ago | bioprocessonline.com | Irwin Hirsh |Q-Specialists AB |Tyler Menichiello |Eric Hennessy

FOCUS ON FACILITIES DESIGN & MAINTENANCELean offers manufacturers a host of efficiencies, but they don't all work for GMP. Here are some ideas for translating best practices for a highly-regulated industry. How Modular Facility Design Can Accelerate GMP Facility ConstructionAutolus Therapeutics' COO talks about the accelerated construction of the company's cell therapy manufacturing facility, The Nucleus.

1 month ago | bioprocessonline.com | Tyler Menichiello

By Tyler Menichiello, contributing editor How does that famous Shakespeare quote go? “To build a brick-and-mortar facility or find a manufacturing partner, that is the question.” Okay, Hamlet may not have been fretting over his company’s manufacturing strategy, but it’s a decision that weighs on most biotech executives’ minds at some point. In my time interviewing industry decision-makers, I’ve heard strong arguments for both.

1 month ago | bioprocessonline.com | Tyler Menichiello |Lauren Parker |Jeffrey Cassel |Mike McManaway

FOCUS ON DOWNSTREAM MANUFACTURINGProcess development experts share their thoughts on continuous manufacturing at this year's BPI West, touching on its benefits and present barriers to adoption. Process Intensification Of Monoclonal Antibody Purification ProcessWatch to explore an intensified mAb purification process that utilizes leading purification technologies, highlighting intensified capture, polishing, and drug delivery.