Articles

  • 1 week ago | bioprocessonline.com | Tyler Menichiello

    By Tyler Menichiello, contributing editor In case you missed it, this month’s Bioprocess Online Live was all about the challenges and special considerations for purifying multispecifics — molecules engineered to engage two or more distinct targets (e.g., bispecific or trispecific antibodies). I was joined by two expert panelists: Mark Fitchmun, president and CEO of Somatek, and Jian Ren, Ph.D., a principal scientist in AbbVie’s manufacturing science and technology (MSAT) bioresearch center.

  • 1 week ago | bioprocessonline.com | Irwin Hirsh |Q-Specialists AB |Tyler Menichiello |Eric Hennessy

    FOCUS ON FACILITIES DESIGN & MAINTENANCELean offers manufacturers a host of efficiencies, but they don't all work for GMP. Here are some ideas for translating best practices for a highly-regulated industry. How Modular Facility Design Can Accelerate GMP Facility ConstructionAutolus Therapeutics' COO talks about the accelerated construction of the company's cell therapy manufacturing facility, The Nucleus.

  • 2 weeks ago | bioprocessonline.com | Tyler Menichiello

    By Tyler Menichiello, contributing editor How does that famous Shakespeare quote go? “To build a brick-and-mortar facility or find a manufacturing partner, that is the question.” Okay, Hamlet may not have been fretting over his company’s manufacturing strategy, but it’s a decision that weighs on most biotech executives’ minds at some point. In my time interviewing industry decision-makers, I’ve heard strong arguments for both.

  • 1 month ago | bioprocessonline.com | Tyler Menichiello |Lauren Parker |Jeffrey Cassel |Mike McManaway

    FOCUS ON DOWNSTREAM MANUFACTURINGProcess development experts share their thoughts on continuous manufacturing at this year's BPI West, touching on its benefits and present barriers to adoption. Process Intensification Of Monoclonal Antibody Purification ProcessWatch to explore an intensified mAb purification process that utilizes leading purification technologies, highlighting intensified capture, polishing, and drug delivery.

  • 1 month ago | bioprocessonline.com | Tyler Menichiello |Ruth Rowland-Jones |Julia Hupfeld |Alison Rees-Manley

    FOCUS ON UPSTREAM MANUFACTURINGWhile continuous processing often steals the spotlight with its promise of uninterrupted workflows, many seasoned professionals continue to advocate for process optimization and intensification as equally effective—and far less capital-intensive—alternatives. From BPI West: An Upstream Scientist's Advice On Target GlycosylationBioprocess Online spoke to an upstream scientist at Bristol Myers Squibb during this year's BPI West. Here's what he had to say.

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