UCB Biosciences

Dec 5, 2024 | onlinelibrary.wiley.com | UCB Biosciences

Plasmodium vivax is responsible for the most widespread form of malaria and approximately 2.5 billion people, or over one-third of the world's population, are at risk of P. vivax infection (Battle et al., 2019). In humans, P. vivax can enter a dormant liver phase, which allows it to survive in various climates, including tropical and temperate regions, and contributes to its extensive geographical prevalence (Battle et al., 2019). P.

Nov 30, 2024 | onlinelibrary.wiley.com | UCB Biosciences |Ithaca College

Burkholderia cenocepacia is a Gram-negative bacterium that is known to be a human pathogen. Due to its inherent antibiotic resistance, ability to form biofilms and virulence factors, this organism is often responsible for life-threatening infections in immunocompromised patients (O'Grady & Sokol, 2011; Scoffone et al., 2016).

Nov 27, 2024 | onlinelibrary.wiley.com | UCB Biosciences

Crystal structure of glutamyl-tRNA synthetase from Helicobacter pylori Dylan E. Davis,a,b‡ Jesuferanmi P. Ayanlade,a,b‡ David T. Laseinde,a,c Sandhya Subramanian,d,e Hannah Udell,d,e Donald J. Lorimer,e,f David M. Dranow,d,f Thomas E. Edwards,d,e Peter J. Mylerd,e and Oluwatoyin A.

Sep 18, 2024 | onlinelibrary.wiley.com | UCB Biosciences

Malaria, a deadly disease caused by protozoan parasites from the Plasmodium genus, poses a significant global health challenge. P. vivax is responsible for the most widespread human malaria and is an obstacle to global malaria-elimination efforts, with nearly 2.5 billion people, or more than one-third of the world's population, at risk of P. vivax infection (Battle et al., 2019). The dormant liver phase of P.

Aug 23, 2024 | onlinelibrary.wiley.com | UCB Biosciences |Biomedical Informatics

Structures of Brucella ovis leucine-, isoleucine-, valine-, threonine- and alanine-binding protein reveal a conformationally flexible peptide-binding cavity Graham Chakafana,a* Reghan Boswell,a Andrew Chandler,a Krishelle A. Jackson,a Sanai Neblett,a Tyler Postal,a Sandhya Subramanian,b,c Jan Abendroth,c,d Peter J. Mylerb,c,e and Oluwatoyin A.