Ula V. Jurkunas

Jul 19, 2024 | mdpi.com | Ula V. Jurkunas

Dec 2, 2023 | cgtlive.com | Ula V. Jurkunas

"This study basically shows that it is feasible to cultivate the stem cells and it is safe. The study does present case reports and how the patients did, however, more definitive statements on the outcomes or the efficacy will be in the next study.”Limbal stem cell (LSC) deficiency, caused by chemical burns, other eye injuries, infection, or hereditary diseases, may result in permanent vision loss, pain, and discomfort.

Oct 21, 2023 | cgtlive.com | Ula V. Jurkunas

"To improve upon the existing procedures, we have developed a technology where only a very small biopsy, such as 1 to 2 millimeters, can be taken from the healthy eye, and the cells are grown in the lab [before transplanting to the diseased eye] and then that way the diseased eye is rehabilitated.”Limbal stem cell (LSC) deficiency can cause permanent vision loss, pain, and discomfort.

Aug 18, 2023 | science.org | Xuan Zheng |Yanran Li |Jiarui Mi |Ula V. Jurkunas

METHODSIn the preclinical phase, cadaveric donor corneas were obtained from the National Disease Research Interchange. Later in the clinical phase, patient limbal biopsies were obtained (surgical details below). For primary (P0) cell culture, a 3 mm–by–3 mm biopsy was harvested from the limbus, and dissected limbal epithelial sheets were digested with Liberase MNP-S (Roche, Basel, Switzerland) and then dissociated into a single-cell suspension.