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Oct 14, 2024 | 
academic.oup.com | De Luca |UMC Utrecht |van der Lelij |Amsterdam UMC
White matter hyperintensities of presumed vascular origin (WMH) are associated with cognitive impairment and are a key imaging marker in evaluating brain health. However, WMH volume alone does not fully account for the extent of cognitive deficits and the mechanisms linking WMH to these deficits remain unclear.
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Sep 8, 2024 | 
link.springer.com | UMC Utrecht
Dear Editor,We thank Dr. Noordman and Dr. Maass for their interest in our study and for highlighting the interesting topic regarding the need for (replacement of) an implantable cardioverter defibrillator (ICD) in idiopathic ventricular fibrillation (iVF) patients [1]. We found similar results as mentioned by the authors regarding appropriate ICD therapy [2, 3].
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May 28, 2024 | 
trialbulletin.com | UMC Utrecht
OverviewInherited cardiovascular conditions generally inherit following an autosomal dominant
pattern. When a mutation is detected in the proband, relatives can have predictive DNA
testing, and – when they are carrier – be monitored and timely treated if needed. Currently,
less than half of relatives attends genetic counselling. With the eCG Family Clinic, an
easily accessible virtual clinic which better suits the needs and preferences of relatives
will be offered.
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Mar 19, 2024 | 
trialbulletin.com | UMC Utrecht
OverviewRSV infection is a leading cause of medical care in older adults, sometimes leading to
hospital admission and severe outcomes. Although the majority of RSV infections are managed
outside hospitals, little is known on the burden of RSV in older adults in the primary care
setting. Accurate estimates of the RSV burden in primary care is particularly relevant since
vaccines against RSV infection in older adults will likely become available for the general
population soon.
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Mar 7, 2024 | 
academic.oup.com | UMC Utrecht
Organoids are 3-dimensional experimental models that summarize the anatomical and functional structure of an organ [1, 2]. Organoids are revolutionizing fundamental and medical research by allowing us to recapitulate human physiology better than animal models, as well as developmental biology contrary to traditional cell cultures [2].
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Feb 7, 2024 | 
trialbulletin.com | UMC Utrecht
OverviewLung perfusion scintigraphy with 99mTc-MAA and ventilation scintigraphy with Technegas (V/Q
SPECT/CT) has been the cornerstone for the detection of pulmonary embolisms (PE) for many
decades.
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Nov 15, 2023 | 
trialbulletin.com | UMC Utrecht
OverviewAlmost 90% of systemic sclerosis (SSc) patients experience hand function limitation, which
leads to impaired daily functioning and work participation. An important cause of impaired
hand function are contractures of the hand, which are reported in up to a half of patients. With this longitudinal cohort study in patients with SSc and VEDOSS (very early diagnosis of
systemic sclerosis) we aim to gain more insight into processes involved in hand function
impairment.
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Sep 26, 2023 | 
trialbulletin.com | UMC Utrecht
OverviewThe goal of the IMPACT project is to set up a data sharing infrastructure between expert
centers for pancreatic surgery that enables training, testing and validation of computer
science tools to improve quality of care for patients with pancreatic cancer. Study Type: ObservationalStudy DesignTime Perspective: RetrospectiveStudy Primary Completion Date: December 31, 2029Detailed DescriptionStudy design: Retrospective, multicenter observational cohort study.
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Jul 18, 2023 | 
trialbulletin.com | UMC Utrecht
OverviewRationale: Osteoarthritis (OA) is mainly characterized by cartilage degeneration. In knee OA,
measuring the distance between the tibia and femur, known as the joint space width (JSW), is
an often-used method to quantify the progression of the disease or the effectiveness of
treatments, because it is an indirect measure of cartilage degeneration.
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Mar 28, 2023 | 
heart.bmj.com | UMC Utrecht
http://orcid.org/0000-0002-2674-8709Steven A Muller1,2, http://orcid.org/0000-0002-4694-4790Anneline S J M te Riele1,2 1Cardiology, UMC Utrecht, Utrecht, The Netherlands 2Netherlands Heart Institute, Utrecht, The Netherlands Correspondence to Dr Anneline S J M te Riele, Cardiology, UMC Utrecht, 3584 CX Utrecht, Netherlands; ariele{at}umcutrecht.nl Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to...
