Valeriya Bezkorovayna

Jun 29, 2024 | biorxiv.org | Brooke K Hayes |Francesca Gillett |Amy Wright |Valeriya Bezkorovayna

AbstractAcinetobacter baumannii is a Gram-negative opportunistic pathogen that is a common cause of nosocomial infections. The increasing development of antibiotic resistance in this organism is a global health concern. The A. baumannii clinical isolate AB307-0294 produces a type VI secretion system (T6SS) that delivers three antibacterial cargo effector proteins (Tse15, Tde16 and Tae17) that give this strain a competitive advantage against other bacteria in polymicrobial environments.